9027 Results for "

Ophiopogon japonicus (L. f.) Ker-Gawl.

" in MedChemExpress (MCE) Product Catalog:
Products (9027)

9027 Results for "Ophiopogon japonicus (L. f.) Ker-Gawl." in MCE Product Catalog:

666
Acetylcysteine
Acetylcysteine
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666 Publications Verification
Art. -Nr.: HY-B0215
CAS. Nr.: 616-91-1
Synonyms: N-Acetylcysteine; N-Acetyl-L-cysteine; NAC
Category:  

Ketones, Aldehydes, Acids Endogenous metabolite

Target:  

Reactive Oxygen Species (ROS) Endogenous Metabolite Apoptosis Ferroptosis Influenza Virus Disulfidptosis

Acetylcysteine (N-Acetylcysteine) is a mucolytic agent that can cross the blood-brain barrier, which reduces the thickness of the mucus. Acetylcysteine is a ROS inhibitor. Acetylcysteine is a cysteine precursor, prevents hemin-induced ferroptosis by neutralizing toxic lipids generated by arachidonate-dependent activity of 5-lipoxygenases. Acetylcysteine induces cell apoptosis. Acetylcysteine also has anti-influenza virus activities. In addition, Acetylcysteine ​​is the most stable form of cysteine ​​during drug delivery and can be used in disulfidptosis studies .
360
Dexamethasone
Dexamethasone
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360 Cited Publications
Art. -Nr.: HY-14648
CAS. Nr.: 50-02-2
Reinheit:  99.86%
Synonyms: Hexadecadrol; Prednisolone F
Target:  

Exosomes Glucocorticoid Receptor SARS-CoV Autophagy Complement System Mitophagy Bacterial Antibiotic ADC Payloads

Forschungsgebiete:  

Infection Cardiovascular Disease Inflammation/Immunology Endocrinology Cancer

Dexamethasone (Hexadecadrol) is a glucocorticoid receptor agonist, apoptosis inducer, and common disease inducer in experimental animals, constructing models of muscle atrophy, hypertension, and depression. Dexamethasone can inhibit the production of inflammatory miRNA-155 exosomes in macrophages and significantly reduce the expression of inflammatory factors in neutrophils and monocytes. Dexamethasone also has potential for use in COVID-19 research .
360
Dexamethasone (Standard)
Dexamethasone (Standard)
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360 Cited Publications
Art. -Nr.: HY-14648R
CAS. Nr.: 50-02-2
Synonyms: Hexadecadrol(Standard); Prednisolone F (Standard)
Target:  

Reference Standards Exosomes Glucocorticoid Receptor SARS-CoV Autophagy Complement System Mitophagy Bacterial Antibiotic ADC Payloads

Forschungsgebiete:  

Infection Inflammation/Immunology Endocrinology Cancer

Dexamethasone (Standard) is the analytical standard of Dexamethasone. This product is intended for research and analytical applications. Dexamethasone (Hexadecadrol) is a glucocorticoid receptor agonist. Dexamethasone also significantly decreases CD11b, CD18, and CD62L expression on neutrophils, and CD11b and CD18 expression on monocytes. Dexamethasone is highly effective in the control of COVID-19 infection. Dexamethasone inhibits production of exosomes containing inflammatory microRNA-155 in lipopolysaccharide-induced macrophage inflammatory responses.
106
Fludarabine
Fludarabine
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106 Cited Publications
Art. -Nr.: HY-B0069
CAS. Nr.: 21679-14-1
Synonyms: F-ara-A; NSC 118218
Target:  

Nucleoside Antimetabolite/Analog DNA/RNA Synthesis STAT Apoptosis

Forschungsgebiete:  

Cancer

Fludarabine (NSC 118218) is a DNA synthesis inhibitor and a fluorinated purine analogue with antineoplastic activity in lymphoproliferative malignancies. Fludarabine inhibits the cytokine-induced activation of STAT1 and STAT1-dependent gene transcription in normal resting or activated lymphocytes .
99
EIPA
EIPA
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99 Cited Publications
Art. -Nr.: HY-101840
CAS. Nr.: 1154-25-2
Reinheit:  99.73%
Synonyms: L593754; MH 12-43; Ethylisopropylamiloride
Target:  

TRP Channel Prostaglandin Receptor Autophagy COX Na+/H+ Exchanger (NHE)

Forschungsgebiete:  

Inflammation/Immunology Cancer

EIPA (L593754) is an orally active TRPP3 channel inhibitor with an IC50 of 10.5 μM. EIPA also enhances autophagy by inhibiting Na +/H +-exchanger 3 (NHE3). EIPA inhibits macropinocytosis as well. EIPA can be used in the research of inflammation and cancers, such as gastric cancer, colon carcinoma, pancreatic carcinoma .
99
EIPA hydrochloride
EIPA hydrochloride
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99 Cited Publications
Art. -Nr.: HY-101840A
CAS. Nr.: 1345839-28-2
Reinheit:  98.31%
Synonyms: L593754 hydrochloride; MH 12-43 hydrochloride; Ethylisopropylamiloride hydrochloride
Target:  

TRP Channel Autophagy COX Prostaglandin Receptor Na+/H+ Exchanger (NHE)

Forschungsgebiete:  

Inflammation/Immunology Cancer

EIPA (L593754) hydrochloride is an orally active TRPP3 channel inhibitor with an IC50 of 10.5 μM. EIPA hydrochloride also enhances autophagy by inhibiting Na +/H +-exchanger 3 (NHE3). EIPA hydrochloride inhibits macropinocytosis as well. EIPA hydrochloride can be used in the research of inflammation and cancers, such as gastric cancer, colon carcinoma, pancreatic carcinoma .
92
Cytochalasin D
Cytochalasin D
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92 Cited Publications
Art. -Nr.: HY-N6682
CAS. Nr.: 22144-77-0
Synonyms: Zygosporin A; NSC 209835
Category:  

Infection Natural Products Microorganisms Disease Research Fields

Target:  

Exosomes Arp2/3 Complex Antibiotic YAP

Cytochalasin D (Zygosporin A) is a potent actin polymerization inhibitor, could be derived from fungus. Cytochalasin D has cell-permeable activity. Cytochalasin D inhibits the G-actin–cofilin interaction by binding to G-actin. Cytochalasin D also inhibits the binding of cofilin to F-actin and decreases the rate of both actin polymerization and depolymerization in living cells. Cytochalasin D can reduce exosome release, in turn reducing the amount of survivin present in the tumour environment. Cytochalasin D induces phosphorylation and cytoplasmic retention of Yap .
88
Genistein
Genistein
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88 Cited Publications
Art. -Nr.: HY-14596
CAS. Nr.: 446-72-0
Reinheit:  99.82%
Synonyms: NPI 031L
Category:  

Anti-aging Plants Endogenous metabolite Human Gut Microbiota Metabolites Flavonoids Microorganisms Leguminosae Glycine max (L.) merr Sunscreen Phenols Polyphenols Cosmetic Research Disease Research Fields Glycyrrhiza uralensis Fisch. Cancer Isoflavones

Target:  

EGFR Autophagy Apoptosis Endogenous Metabolite

Genistein, a soy isoflavone, is a multiple tyrosine kinases (e.g., EGFR) inhibitor which acts as a chemotherapeutic agent against different types of cancer, mainly by altering apoptosis, the cell cycle, and angiogenesis and inhibiting metastasis.
88
Genistein (Standard)
Genistein (Standard)
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88 Cited Publications
Art. -Nr.: HY-14596R
CAS. Nr.: 446-72-0
Reinheit:  99.31%
Synonyms: NPI 031L (Standard)
Category:  

Anti-aging Plants Endogenous metabolite Human Gut Microbiota Metabolites Flavonoids Leguminosae Glycine max (L.) merr Sunscreen Phenols Cosmetic Research Disease Research Fields Glycyrrhiza uralensis Fisch. Cancer

Target:  

Reference Standards EGFR Autophagy Apoptosis Endogenous Metabolite

Genistein (Standard) is the analytical standard of Genistein. This product is intended for research and analytical applications. Genistein, a soy isoflavone, is a multiple tyrosine kinases (e.g., EGFR) inhibitor which acts as a chemotherapeutic agent against different types of cancer, mainly by altering apoptosis, the cell cycle, and angiogenesis and inhibiting metastasis.
81
L-Ascorbic acid
L-Ascorbic acid
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81 Cited Publications
Art. -Nr.: HY-B0166
CAS. Nr.: 50-81-7
Synonyms: L-Ascorbate; Vitamin C
Category:  

Natural Products Neurological Disease Moringa oleifera Lam. Metabolic Disease Endocrine diseases Plants Endogenous metabolite Disease markers Moringaceae Nervous System Disorder Disease Research Fields

Target:  

Environmental Pollutants Endogenous Metabolite Calcium Channel Reactive Oxygen Species (ROS) Apoptosis

L-Ascorbic acid (L-Ascorbate), an electron donor, is an endogenous antioxidant agent. L-Ascorbic acid inhibits selectively Cav3.2 channels with an IC50 of 6.5 μM. L-Ascorbic acid is also a collagen deposition enhancer and an elastogenesis inhibitor . L-Ascorbic acid exhibits anti-cancer effects through the generation of reactive oxygen species (ROS) and selective damage to cancer cells .
81
L-Ascorbic acid sodium salt
L-Ascorbic acid sodium salt
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81 Cited Publications
Art. -Nr.: HY-B0166A
CAS. Nr.: 134-03-2
Synonyms: Sodium ascorbate; Sodium L-ascorbate; Vitamin C sodium salt
Category:  

Natural Products other families Plants Disease Research Fields Cancer

Target:  

Environmental Pollutants Apoptosis Endogenous Metabolite Calcium Channel Reactive Oxygen Species (ROS)

L-Ascorbic acid sodium salt (Sodium ascorbate), an electron donor, is an endogenous antioxidant agent. L-Ascorbic acid sodium salt selectively inhibits Cav3.2 channels with an IC50 of 6.5 μM. L-Ascorbic acid sodium salt is also a collagen deposition enhancer and an elastogenesis inhibitor .
79
L-NAME hydrochloride
L-NAME hydrochloride
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79 Cited Publications
Art. -Nr.: HY-18729A
CAS. Nr.: 51298-62-5
Synonyms: NG-Nitroarginine methyl ester hydrochloride
Target:  

NO Synthase

Forschungsgebiete:  

Infection Neurological Disease Cancer

L-NAME hydrochloride inhibits NOS with an IC50 of 70 μM. L-NAME is a precursor to NOS inhibitor L-NOARG which has an IC50 value of 1.4 μM. L-NAME hydrochloride requires hydrolysis of the methyl ester by cellular esterases to become a fully functional inhibitor. L-NAME hydrochloride can be used to induce hypertension and preeclampsia models.
74
L-Ascorbic acid calcium dihydrate
L-Ascorbic acid calcium dihydrate
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74 Cited Publications
Art. -Nr.: HY-B0166C
CAS. Nr.: 5743-28-2
Synonyms: L-Ascorbate calcium dihydrate; Vitamin C calcium dihydrate
L-Ascorbic acid (calcium dihydrate) (L-Ascorbate (calcium dihydrate); Vitamin C (calcium dihydrate)) is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
62
Reparixin L-lysine salt
Reparixin L-lysine salt
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62 Cited Publications
Art. -Nr.: HY-15252
CAS. Nr.: 266359-93-7
Reinheit:  99.87%
Synonyms: Repertaxin L-lysine salt
Target:  

CXCR

Forschungsgebiete:  

Inflammation/Immunology Endocrinology Cancer

Reparixin L-lysine salt is an allosteric inhibitor of chemokine receptor 1/2 (CXCR1/2) activation.
62
Norepinephrine
Norepinephrine
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62 Cited Publications
Art. -Nr.: HY-13715
CAS. Nr.: 51-41-2
Reinheit:  99.61%
Synonyms: Levarterenol; L-Noradrenaline
Category:  

Cardiovascular Disease Phenols Polyphenols Endogenous metabolite Disease Research Fields

Target:  

Endogenous Metabolite Adrenergic Receptor Autophagy

Norepinephrine (Levarterenol; L-Noradrenaline) is a potent adrenergic receptor (AR) agonist. Norepinephrine activates α1, α2, β1 receptors .
62
Norepinephrine hydrochloride
Norepinephrine hydrochloride
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62 Cited Publications
Art. -Nr.: HY-13715A
CAS. Nr.: 329-56-6
Reinheit:  99.89%
Synonyms: Levarterenol hydrochloride; L-Noradrenaline hydrochloride
Category:  

Cardiovascular Disease Alkaloids Leguminosae Mimosa pudica Linn. Other Alkaloids Phenols Polyphenols Plants Disease Research Fields Endocrinology

Target:  

Adrenergic Receptor Autophagy Endogenous Metabolite

Norepinephrine (Levarterenol; L-Noradrenaline) hydrochloride is a potent adrenergic receptor (AR) agonist. Norepinephrine activates α1, α2, β1 receptors .
62
Norepinephrine bitartrate monohydrate
Norepinephrine bitartrate monohydrate
0 Images
62 Cited Publications
Art. -Nr.: HY-13715B
CAS. Nr.: 108341-18-0
Reinheit:  99.96%
Synonyms: Levarterenol bitartrate monohydrate; L-Noradrenaline bitartrate monohydrate
Category:  

Phenols Endogenous metabolite Disease Research Fields Endocrinology

Target:  

Adrenergic Receptor Autophagy Endogenous Metabolite

Norepinephrine (Levarterenol; L-Noradrenaline) bitartrate monohydrate is a potent adrenergic receptor (AR) agonist. Norepinephrine activates α1, α2, β1 receptors .
62
Norepinephrine tartrate
Norepinephrine tartrate
0 Images
62 Cited Publications
Art. -Nr.: HY-13715C
CAS. Nr.: 51-40-1
Reinheit:  99.76%
Synonyms: Levarterenol tartrate; L-Noradrenaline tartrate
Category:  

Cardiovascular Disease Phenols Polyphenols Endogenous metabolite Disease Research Fields

Target:  

Endogenous Metabolite Adrenergic Receptor Autophagy

Norepinephrine (Levarterenol; L-Noradrenaline) tartrate is a potent adrenergic receptor (AR) agonist. Norepinephrine tartrate activates α1, α2, β1 receptors .
57
5-Ph-IAA
5-Ph-IAA
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57 Cited Publications
Art. -Nr.: HY-134653
CAS. Nr.: 168649-23-8
Reinheit:  99.51%
Target:  

Epigenetic Reader Domain

Forschungsgebiete:  

Cancer

5-Ph-IAA is a derivative of IAA. 5-Ph-IAA, a ligand, establishes the auxin-inducible degron 2 (AID2) system together with an OsTIR1 (F74G) mutant. AID2 induces rapid and efficient depletion of mAID-fused proteins to study protein function in living cells, causing tumor suppression .
57
IL-1 beta Protein, Human
IL-1 beta Protein, Human
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57 Cited Publications
Art. -Nr.: HY-P7028
Reinheit:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: rHuIL-1β; Catabolin; IL1F2; IL-1 beta; IL1B
Species:  
Human
Source:  
E. coli
Assay Types